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David Komatsu, Ph.D.

Komatsu, David website big Senior Scientist/Manager, Biologics/Biomaterials Laboratory

Education

Ph.D. Biomedical Engineering

M.S. Biomedical Engineering

Stony Brook University, Stony Brook, New York

B.A. Psychology

University of California, Santa Barbara, California

Experience

Post-Doctorate Fellow, Integrative Biology

Eli Lily and Company, Indianapolis, Indiana

Orthopaedics Research Laboratory, Indiana University, Caramel, Indiana

Research Assistant, Molecular & Cellular Bioengineering Lab

Stony Brook University, Stony Brook, New York

Expertise

Animal models

Gel electrophoresis histology

Immunohistochemistry/precipitation

Gene cloning

Micro computed tomography

Microscopy

Northern and Western blots

Recombinant and fusion proteins

RNA, DNA protein isolation

Tissue culture

Patents

Mustang, a gene and nuclear protein. US Patent #7,238,799.

Publications

Komatsu DE, Bosch-Marce M, Semenza GL, Hadjiargyrou, M. Enhanced Bone Regeneration Associated with Decreased Apoptosis in Mice with Partial HIF-1alpha Deficiency. J Bone Miner Res. 2007; 22: 366-374.

Komatsu DE, Hadjiargyrou M. Activation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair. Bone. 2004; 34:680-688.

Lombardo, F., Komatsu, D. and Hadjiargyrou, M.  Molecular cloning and characterization of Mustang, a novel nuclear protein expressed during skeletal development and regeneration. The FASEB Journal. 2004; 18: 52-61.




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InMotion Musculoskeletal Institute | 20 South Dudley, Suite 700 | Memphis, TN 38103 | 901-271-0000